From I-4 East: If You're Traveling Westbound On I-4, Take Exit 1 For 21St Street Toward Ybor City. I4highway Continue On 21St Street: After Exiting, Turn Left Onto 21St Street. Turn Onto E 27Th Avenue: Proceed North On 21St Street, Then Turn Right Onto E 27Th Avenue. Your Destination, 2622 E 27Th Ave, Will Be On The Left.